Molecular target
5-HT1D Receptor
Serotonin receptor on trigeminal nerve terminals; agonism reduces release of pro-inflammatory neuropeptides (CGRP, substance P) implicated in migraine pathophysiology. Co-targeted with 5-HT1B by triptans.
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Pharmaceutical agents
Drugs that act on 5-HT1D Receptor
These medications have 5-HT1D Receptor among their molecular targets. Sharing a target is a mechanistic relationship — it does not make any plant below an alternative to, or substitute for, these drugs.