Molecular target
CB1 Cannabinoid Receptor
Also: CNR1 · id CB1
Predominantly central nervous system cannabinoid receptor; mediates psychoactive effects of THC and is implicated in pain, appetite, mood, and memory.
Educational use only. This page summarizes published research and traditional-use records for educational purposes. It does not diagnose, treat, cure, or prevent any disease. Do not start, stop, or change medications based on this information. Discuss any decisions about therapies — pharmaceutical or botanical — with a qualified clinician who knows your medical history.
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Pharmaceutical agents
Drugs that act on CB1 Cannabinoid Receptor
These medications have CB1 Cannabinoid Receptor among their molecular targets. Sharing a target is a mechanistic relationship — it does not make any plant below an alternative to, or substitute for, these drugs.
Botanical connections
Plants whose compounds act on CB1 Cannabinoid Receptor
Each plant below contains a named compound documented to act on CB1 Cannabinoid Receptor. The compound and the reason for the connection are shown on every edge — a shared mechanism, not a therapeutic equivalence.
- Δ9-Tetrahydrocannabinol (THC)Psychoactive cannabinoid
Partial agonist at CB1 (psychoactivity, analgesia, appetite, memory effects) and CB2 (anti-inflammatory, immune).
- Cannabigerol (CBG)Cannabinoid (parent)
Precursor cannabinoid with weak CB1/CB2 partial agonism and α2-adrenergic activity. Lower psychoactivity than THC.