Molecular target
Cyclin-Dependent Kinases / Cell Cycle
Also: CDK4/6, Cell-Cycle Regulation · id CDK
Cyclin-dependent kinases governing cell-cycle progression; CDK4/6-inhibitor drugs (palbociclib, ribociclib, abemaciclib) arrest proliferation in hormone-receptor-positive cancers. Certain flavonoids (apigenin, luteolin, fisetin) have been investigated for cell-cycle-arrest activity in preclinical studies.
Educational use only. This page summarizes published research and traditional-use records for educational purposes. It does not diagnose, treat, cure, or prevent any disease. Do not start, stop, or change medications based on this information. Discuss any decisions about therapies — pharmaceutical or botanical — with a qualified clinician who knows your medical history.
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Pharmaceutical agents
Drugs that act on Cyclin-Dependent Kinases / Cell Cycle
These medications have Cyclin-Dependent Kinases / Cell Cycle among their molecular targets. Sharing a target is a mechanistic relationship — it does not make any plant below an alternative to, or substitute for, these drugs.
Botanical connections
Plants whose compounds act on Cyclin-Dependent Kinases / Cell Cycle
Each plant below contains a named compound documented to act on Cyclin-Dependent Kinases / Cell Cycle. The compound and the reason for the connection are shown on every edge — a shared mechanism, not a therapeutic equivalence.
- ApigeninFlavone
Apigenin binds GABA-A at the benzodiazepine site (its anxiolytic mechanism) and has separately been investigated for cyclin-dependent-kinase-mediated cell-cycle arrest in preclinical cancer models. Research only — not a treatment claim.