Molecular target
Dopamine Transporter
Also: SLC6A3 · id DAT
Reuptake transporter for dopamine; targeted by stimulants and weakly by some SSRIs (e.g., sertraline) and adaptogens.
Educational use only. This page summarizes published research and traditional-use records for educational purposes. It does not diagnose, treat, cure, or prevent any disease. Do not start, stop, or change medications based on this information. Discuss any decisions about therapies — pharmaceutical or botanical — with a qualified clinician who knows your medical history.
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Pharmaceutical agents
Drugs that act on Dopamine Transporter
These medications have Dopamine Transporter among their molecular targets. Sharing a target is a mechanistic relationship — it does not make any plant below an alternative to, or substitute for, these drugs.
Botanical connections
Plants whose compounds act on Dopamine Transporter
Each plant below contains a named compound documented to act on Dopamine Transporter. The compound and the reason for the connection are shown on every edge — a shared mechanism, not a therapeutic equivalence.
- CathinonePhenylalkylamine alkaloid
Primary psychoactive constituent; structurally and pharmacologically analogous to amphetamine. Research indicates it may promote monoamine release and inhibit reuptake at DAT, NET, and SERT, and may inhibit MAO-A and MAO-B. Degrades rapidly on storage, which is why leaves are chewed fresh.
- L-DOPACatecholamine precursor (amino acid)
Direct levodopa — chemically identical to the prescription drug. After hepatic + CNS decarboxylation, L-DOPA becomes dopamine, raising D1/D2 activity. The reason Mucuna is functionally a Parkinson’s drug, not a supplement.