Molecular target
Microtubule (β-Tubulin)
Cytoskeletal polymer essential for cell division and intracellular transport. Disruption by colchicine (depolymerization) treats acute gout via inhibition of neutrophil migration. Plant alkaloid colchicine itself comes from Colchicum autumnale (autumn crocus); the more familiar plant tubulin-binders are vincristine/vinblastine (Vinca rosea) and paclitaxel (Pacific yew, Taxus brevifolia) — among the most clinically successful plant-derived oncology drugs.
Educational use only. This page summarizes published research and traditional-use records for educational purposes. It does not diagnose, treat, cure, or prevent any disease. Do not start, stop, or change medications based on this information. Discuss any decisions about therapies — pharmaceutical or botanical — with a qualified clinician who knows your medical history.
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Pharmaceutical agents
Drugs that act on Microtubule (β-Tubulin)
These medications have Microtubule (β-Tubulin) among their molecular targets. Sharing a target is a mechanistic relationship — it does not make any plant below an alternative to, or substitute for, these drugs.
Botanical connections
Plants whose compounds act on Microtubule (β-Tubulin)
Each plant below contains a named compound documented to act on Microtubule (β-Tubulin). The compound and the reason for the connection are shown on every edge — a shared mechanism, not a therapeutic equivalence.
- Deoxypodophyllotoxin
Deoxypodophyllotoxin (a podophyllotoxin analog isolated here from an endophytic Aspergillus fumigatus associated with juniper) is a well-documented microtubule/β-tubulin inhibitor that blocks tubulin polymerization, the defining antimitotic mechanism of the podophyllotoxin class. Compound-specific and well-studied.